Foot and Ankle
Sayyed-Hadi Sayyed-Hosseinian; Farshid Bagheri; Reza pourali; Ehsan Vahedi; Ali Birjandinejad; Mohammad Hosein Ebrahimzadeh
Abstract
Background: Ankle arthrodesis is one of the major surgeries for the treatment of advanced osteoarthritis of the ankle joint. There are various techniques available for ankle arthrodesis and each technique has unique advantages and disadvantages. The aim of the present study was to evaluate the results ...
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Background: Ankle arthrodesis is one of the major surgeries for the treatment of advanced osteoarthritis of the ankle joint. There are various techniques available for ankle arthrodesis and each technique has unique advantages and disadvantages. The aim of the present study was to evaluate the results of ankle arthrodesis with two this different approaches.Methods: The medical records of the patients who were admitted for ankle arthrodesis and treated by a single surgeon from January 2015 to January 2020 were reviewed. The patients were recalled for re-evaluation after a mean follow-up of 19 months. Functional outcomes were assessed using validated AOFAS Ankle-Hind foot score, Manchester-Oxford Foot Questionnaire (MOXFQ) and visual analog scale (VAS) score for pain. The collected data were recorded in a pre-designed checklist and then analyzed using SPSS software.Results: A total of 32 patients, 18 men and 14 women with a mean age of 46.7 years were included in the study. 67.6% had history of ankle fractures. Anterior approach was used in 24 patients, 75%, and the rest of the patients had surgery with lateral approach (25%). The most common instrument for arthrodesis was concomitant use of plate and screws in 18 patients (56%). Union occurred in 28 patients (87.5%) within 11.1 weeks after the surgery. The AOFAS score increased significantly and MOXFQ and VAS scores decreased significantly following the surgery (p<0.001 for each). Advanced age and intramedullary nail were related to prolonged time to union (p<0.05). Surgical approaches (either anterior or lateral) had no association with AOFAS, MOXFQ, and VAS scores. Non-union was seen in 4 patients (12.5%) and deep infection in 3 patients (9.3%) after ankle arthrodesis.Conclusion: The study results showed that, this surgery could improve patients’ pain and function with relatively low post-operative complications.
Amin Razi; Mohammad taghi Peivandi; Ali Birjandinejad; Sara Amel Farzad
Abstract
Abstract
Background: Nonunion is a serious complication following long-bone fracture that is known as a therapeutic challenge for surgeons and is associated with significant morbidity. It has been shown that osteogenesis stimulating factors combined with optimization of the mechanical environment could ...
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Abstract
Background: Nonunion is a serious complication following long-bone fracture that is known as a therapeutic challenge for surgeons and is associated with significant morbidity. It has been shown that osteogenesis stimulating factors combined with optimization of the mechanical environment could facilitate and accelerate nonunion healing. In this study, we aimed to treat nonunion using autologous bone marrow-derived mononuclear cell (BMDMC) aspirate as a source of osteoprogenitor cells combined with internal fixation.
Methods: From November 2010 to May 2013, 19 cases of nonunion were treated with bone marrow-derived mononuclear cell (BMDMC) grafting, that included 15 males and 4 females with an average age of 37.8 years (range, 18-81 years). The time from injury to therapy was 7 to 28 months, with an average of 13.4 months. At first, decortications were performed around the nonunion site to prepare a suitable bed for bone marrow grafting. Then, 2 ml of bone marrow concentrated cells was applied to the nonunion site in a mixture with partially demineralized cortical cancellous allograft chips. The healing rate in each patient was clinically and radiologically evaluated every 4 weeks.
Results: Bone union was obtained in 18 of the 19 patients during 1.06 to 6 months with an average time of 3.5 months. No complications during anesthesia nor any infection, hematoma or chronic pain at the nonunion site were observed in any patient.
Conclusion: Transplantation of autologous BMDMC aspirate is a reasonable, effective and easy treatment option for tibial and femoral nonunion after internal fixation.
Trial registration: This study has been registrated in ClinicalTrials.gov (https://clinicaltrials.gov).
TRN:NCT01788059
Seyed Hadi Seyed Hoseinian; Farshid Bagheri; Ali Birjandi Nejad; Mohammad Taghi Peivandi; Mohammad-Hosien Ebrahimzadeh
Abstract
AbstractAbstractBackground: The aim of this study was to investigate the prevalence of Hepatitis B(HBV),Hepatitis C( HCV),and Human immunodeficiency virus(HIV)in a large trauma center in northeast of Iran.Methods: In a descriptive cross sectional study, 27252 consecutive patients admitted in a trauma ...
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AbstractAbstractBackground: The aim of this study was to investigate the prevalence of Hepatitis B(HBV),Hepatitis C( HCV),and Human immunodeficiency virus(HIV)in a large trauma center in northeast of Iran.Methods: In a descriptive cross sectional study, 27252 consecutive patients admitted in a trauma hospital in Mashhad, Iran during March 2012 to March 2017 who required surgery for their traumatic injuries were screened for the presence of Hepatitis B surface antigen (HBsAg), anti HCV Ab and anti HIV Ab.Results: In 926 patients at least one of the serologic tests was positive, showing an incidence of 3.3% seropositivity among study population. HBsAg was positive in 523 patients (1.9%), HCV Ab in 388 (1.4%) and HIV Ab in 15 patients (0.05%) respectively. 19 patients (0.06%) were simultaneously infected by more than one virus.Conclusion: The results of this study demonstrate that seroprevalence of blood born-pathogens among trauma patients, especially HCV and HIV, are higher than general population and it emphasized that health care workers in trauma centers must adhere to standard precautions to prevent viral transmission.Level of Clinical Evidence:4
amin razi; Mohammad-Taghi Peivandi; Ali Birjandinejad; Ali Parsa; Sara Amel Farzad; Maryam Hosseini Hasanabady
Abstract
Orthopaedics tissues, such as bone, cartilage, and tendon, involve cells that are difficult to culture and grow in vitro for reconstruction of damaged tissues. A small number of cells called stem cells have the ability to self-renew and differentiate into connective tissue lineages, involving bone, cartilage, ...
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Orthopaedics tissues, such as bone, cartilage, and tendon, involve cells that are difficult to culture and grow in vitro for reconstruction of damaged tissues. A small number of cells called stem cells have the ability to self-renew and differentiate into connective tissue lineages, involving bone, cartilage, tendon and ligaments. Recent development in stem cell research has led to an exciting effort in applying stem cells for orthopaedics tissue regeneration. This review summarizes recent findings regarding the potential clinical use of Mesenchymal Stem Cells (MSCs) in Non:union:s, Osteogenesis imperfect, Human Cartilage defects, Osteoarthritis and Rheumatoid arthritis to provide a better understanding of the issue engineering with stem cell research, as well as the potential therapeutic purpose of these cells in orthopedic surgery.
